A - Human Necessities – 61 – J
Patent
A - Human Necessities
61
J
A61J 3/02 (2006.01) A61K 9/16 (2006.01) A61K 31/519 (2006.01)
Patent
CA 2390563
An emulsion is formed by combining two phases in a static mixer (140, 235). The outflow of the blending static mixer (130,230). The emulsion is conbined with an extraction liquid in a blending static mixer is combined with additional extraction liquid. The additional extraction liquid and the outlfow of the blending static mixer can be combined in a vessel (160), or through the use of a static mixer manifold (240) that includes a plurality of static mixers.
L'invention concerne un appareil et un procédé de préparation de microparticules au moyen d'une extraction directe par solvant. On constitue une émulsion en combinant deux phases dans un mélangeur statique (130, 230). L'émulsion est combinée au liquide d'extraction dans un mélangeur statique de mélange (140, 235). L'écoulement dudit mélangeur statique est combiné au liquide d'extraction supplémentaire. Ce liquide et l'écoulement dudit mélangeur statique peuvent être associés dans une cuve (160), ou par le biais de l'utilisation d'un collecteur (240) de mélangeur statique qui comprend plusieurs mélangeurs statiques.
Lyons Shawn L.
Wright Steven G.
Alkermes Inc.
Alkermes Controlled Therapeutics Inc. II
Smart & Biggar
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