B - Operations – Transporting – 01 – L
Patent
B - Operations, Transporting
01
L
B01L 3/02 (2006.01) B01J 19/00 (2006.01) G01N 35/10 (2006.01) G01N 35/00 (2006.01)
Patent
CA 2361835
The present invention provides a method and apparatus for dispensing a small volume of a selected liquid, such as a biological sample or reagent, onto a substrate. The device includes a tube adapted to contain the liquid. An elongate fiber is disposed within the tube for axial movement therein between raised and lowered positions. Upon shifting or oscillating the fiber between its raised and lowered positions, a liquid spot can be formed at a selected position on the substrate. The device is readily adaptable for the production of micro-arrays having a great number of individual spots.
L'invention concerne un procédé et un dispositif qui permettent de dispenser un petit volume d'un liquide sélectionné, tel qu'un échantillon biologique ou un réactif, sur un substrat. Le dispositif comprend un tube conçu pour contenir un liquide. Une fibre allongée est disposée à l'intérieur du tube, de façon à se déplacer axialement à l'intérieur dudit tube entre une position haute et une position basse. Le décalage ou l'oscillation de la fibre entre lesdites positions permet de former une tache de liquide à une position choisie sur le substrat. Le dispositif peut s'adapter rapidement à la production de micro-réseaux comportant un grand nombre de taches distinctes.
Bryning Zbigniew
Vann Charles S.
Applera Corporation
Pe Corporation (ny)
Sim & Mcburney
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