Apparatus and method for taking the derivative of a slowly...

Details Apparatus and method for taking the derivative of a slowly... Apparatus and method for taking the derivative of a slowly...

G - Physics

06

G

354/153, 73/164,

G06G 7/18 (2006.01) G06G 7/184 (2006.01)

Patent

CA 1058759

Abstract of the Disclosure An electrical circuit for operating upon a slowly varying input signal (on the order of one volt per minute) to provide as output signal representative of the input signal derivative. The circuitry employs at least two feedback loops, one of which is constructed similar to an integrator amplifier. One particularly useful electro-medical application of this appar- atus and method lies in the measurement of osmotic fragility of red blood cells, where percentage hemolysis of the blood slowly varies as a function of tonicity of suspension of the medium in which the blood sample is suspended. In this measurement the exact point of maximum slope is important and is provided by the present invention.

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