Apparatus and method for the production of frozen beads

F - Mech Eng,Light,Heat,Weapons – 25 – C

Patent

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Details

F25C 1/00 (2006.01) B01J 2/06 (2006.01) B01J 19/06 (2006.01) G01N 1/42 (2006.01)

Patent

CA 2437341

An apparatus (10) and method for producing dry beads of a liquid reagent for use in various methods of analysis. The beads are formed by use of an x-y table (18) that can be translated along both the x and the y axis. An insulated tray (20) containing liquid cryogen is positioned atop the x-y table. A metal grid (24) forms a plurality of cells (22) in the tray so that the cryogen is free to enter the cells (22) up to the level of the cryogen in the tray (20). The frozen drops form into beads and freely amass on the bottom of the tray (20). A drop forming device (34) dispenses individual drops to fall by gravity into an individual, discrete cell (22). The table (18) then translates to position another discrete cell (22) for receiving the subsequent drop of reagent. The movement of the x-y table (18) causes agitation of the cryogen to enhance the freezing process.

L'invention se rapporte à un appareil et un procédé de production de billes sèches d'un réactif liquide utilisé dans de nombreuses méthodes d'analyse. Ces billes sont fabriquées au moyen d'une table x-y qui peut être transférée le long des deux axes x et y. Un plateau isolant contenant un cryogène liquide est placé au-dessus de ladite table. Une grille métallique forme une pluralité de cellules sur le plateau de manière que le cryogène puisse librement pénétrer les cellules jusqu'à atteindre le niveau de cryogène du plateau. Les gouttes congelées se transforment en billes et s'amoncellent librement sur le fond du plateau. Un dispositif de formation de goutte provoque la chute des gouttes, par gravité, dans une cellule discrète individuelle. La table change alors la position d'une autre cellule discrète afin que cette dernière puisse recevoir la goutte de réactif. Le déplacement de la table x-y entraîne un mouvement du cryogène qui améliore le processus de congélation.

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