Apparatus and method for transdermal delivery of influenza...

A - Human Necessities – 61 – K

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A61K 39/145 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2562932

An apparatus and method for transdermally delivering an immunologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of micrpojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers, the micrprojection member having a biocompatible coating disposed thereon that includes the immunologically active agent. Preferably, the biocompatible coating is formed from a vaccine coating formulation.

L'invention concerne un appareil et une méthode d'administration par voie transdermique d'un agent immunologiquement actif. L'appareil comprend un système d'administration pourvu d'un dispositif (ou système) de micro-saillies contenant une pluralité de micro-saillies (ou réseau de micro-saillies) adaptées pour percer la couche cornée de la couche épidermique sous-jacente, ou les couches de l'épiderme et du derme. Ledit dispositif à micro-saillies est revêtu d'un revêtement biocompatible contenant l'agent immunologiquement actif. Le revêtement biocompatible est, de préférence, obtenu à partir d'une formulation de revêtement pour vaccin.

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