Apparatus and methods for affinity capture tandem mass...

H - Electricity – 01 – J

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H01J 49/16 (2006.01) G01N 30/72 (2006.01) H01J 49/04 (2006.01) H01J 49/40 (2006.01)

Patent

CA 2425456

The invention provides an analytical instrument comprising an affinity capture probe interface, a laser desorption ionization source, and a tandem mass spectrometer. Also presented are new methods for protein discovery and identification and for characterization of molecular interactions that utilize the instrument of the present invention.

L'invention concerne un instrument d'analyse comportant une interface à sonde de détection d'affinité, une source d'ionisation à désorption laser, et un spectromètre de masse en tandem. L'invention concerne également des procédés faisant appel à cet instrument pour la découverte et l'identification de protéines ainsi que pour la caractérisation d'interactions moléculaires.

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