Apparatus and methods for amplification of blood stem cell...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/0789 (2010.01) C12N 5/078 (2010.01) A61K 35/14 (2006.01) A61K 48/00 (2006.01) C12M 1/00 (2006.01) C12M 3/00 (2006.01) C12N 1/04 (2006.01)

Patent

CA 2565581

The present invention provides an apparatus and methods for expansion of hematopoietic stem cell numbers. The stem cells are cultured and differentiated cells and endogenous growth factors are removed (depleted), permitting long term culture and expansion of the stem cells. The hematopoietic stem cells are used in numerous therapeutic procedures.

L'invention porte sur un appareil et des procédés destinés à augmenter le nombre de cellules souches hématopoïétiques multipotentes. Les cellules souches sont des cellules cultivées et différenciées dans lesquelles les facteurs de croissance endogènes sont éliminés (appauvris), ce qui permet d'obtenir des cultures à long terme et une augmentation du nombre de cellules souches. Les cellules souches hématopoïétiques sont utilisées dans de nombreuses procédures thérapeutiques.

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