B - Operations – Transporting – 01 – J
Patent
B - Operations, Transporting
01
J
B01J 19/00 (2006.01) B01L 3/00 (2006.01) B01L 3/02 (2006.01) C07G 3/00 (2006.01) G01R 1/067 (2006.01) C07B 61/00 (2006.01) G01N 1/00 (2006.01)
Patent
CA 2297681
A method for depositing biomolecule onto a solid support, the method including the steps of: immersing a tip of a spring probe into a solution of biomolecule; removing said tip from said solution to provide biomolecule solution adhered to said tip; and contacting said biomolecule solution with a solid support to thereby transfer biomolecule solution from said tip to said solid support. The spring probe has a planar tip but it is otherwise identical to commercial spring probes. The solution of biomolecule contains a thickening agent in addition to biomolecule, where oligonucleotide is a preferred biomolecule.
Cette invention se rapporte à un procédé qui permet de déposer une biomolécule sur un support solide et qui consiste: à immerger la pointe d'une sonde à ressort dans une solution de biomolécule; à retirer ladite sonde de ladite solution, pour amener la solution de biomolécule à adhérer à ladite pointe; et à mettre cette solution de biomolécule en contact avec un support solide, pour faire passer la solution de biomolécule de la pointe au support solide. La sonde à ressort comprend une pointe plane mais elle est pour le reste identique aux sondes à ressort disponibles dans le commerce. La solution de biomolécule contient un agent épaississant en plus de la biomolécule et la biomolécule préférée est un oligonucléotide.
Moynihan Kristen
Tabone John C.
Van Ness Jeffrey
Gowling Lafleur Henderson Llp
Rapigene Inc.
Rapigene Inc.
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