Apparatus and methods for automated handling and embedding...

G - Physics – 01 – N

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G01N 1/00 (2006.01) B32B 5/02 (2006.01) G01N 1/36 (2006.01) G01N 35/00 (2006.01)

Patent

CA 2491999

An automated machine (10) for handling and embedding tissue samples (210) contained on microtome sectionable supports. The machine (10) includes an input member (100) configured to hold a pluralitz of the microtome sectionable supports (150a) prior to a tissue embedding operation. An output member (32a- 32d) is configured to hold a plurality of the microtome sectionable supports (150a) after the tissue embedding operation. A cooling unit (80) is configured to hold at least one of the microtome sectionable supports (150a) during the tissue embedding operation. A motorized carrier assembly (40) is mounted for movement and configured to hold at least one of the microtome sectionable supports (150a). The carrier assembly (40) moves the support (150a) from the input member (100) to the cooling unit (80) and, finally, to the output member ( 32a-32d). A dispensing device (212) dispenses an embedding material (205) onto the microtome sectionable support (150a) and at least one tissue sample (210) carried by the microtome sectionable support (150a) during the embedding operation.

L'invention concerne une machine automatique (10) de manipulation et d'enrobage d'échantillons (210) de tissus placés sur des supports de microtome sectionnables. La machine (10) comprend un élément (100) d'entrée configuré pour recevoir une pluralité de supports de microtome sectionnables (150a) avant une opération d'enrobage de tissu. Un élément (32a-32d) est configuré pour recevoir une pluralité de supports de microtome sectionnables (150a) après une opération d'enrobage de tissu. Une unité (80) de refroidissement est configurée pour recevoir au moins un des supports de microtome sectionnables (150a) au cours de l'opération d'enrobage du tissu. Un ensemble (40) de transport motorisé est monté pour être déplacé et configuré pour recevoir au moins un des supports de microtome sectionnables (150a). L'ensemble (40) de transport déplace le support (150a) de l'élément (100) d'entrée vers l'unité (80) de refroidissement et, enfin, vers l'élément ( 32a-32d) de sortie. Un dispositif (212) de distribution distribue un matériau (205) d'enrobage sur le support de microtome sectionnable (150a) et au moins un échantillon (210) de tissu porté par le support de microtome sectionnable (150a) au cours de l'opération d'enrobage.

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