Apparatus and methods for detecting nucleic acid in...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C12M 1/40 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2542518

There are disclosed apparatus and methods for the field-assisted acceleration of biological processes involving charged entities, including in particular the detection of target DNA in a biological sample. A reaction cell is provided with a dielectric surface, and a field is generated by inducing charge-separation in the dielectric material by applying a potential to an electrode in contact with the dielectric material.

L'invention concerne des dispositifs et des procédés pour l'accélération, à assistance de champ, de procédés biologiques faisant intervenir des entités chargées, y compris en particulier la détection d'ADN cible dans un échantillon biologique. On établit une cellule de réaction avec une surface diélectrique, puis on produit un champ en induisant une séparation de charge dans le matériau diélectrique par application d'un potentiel à une électrode en contact avec ledit matériau.

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