A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 5/32 (2006.01) A61L 29/14 (2006.01) A61L 29/16 (2006.01) A61M 5/14 (2006.01) A61M 5/172 (2006.01) A61M 25/00 (2006.01) A61M 39/08 (2006.01)
Patent
CA 2388536
Apparatus and methods for delivery of a drug or compound (25) into a fluid flowing within a tube or catheter (20). In one embodiment a catheter includes an inner surface coated with a polymer matrix (55) such as a hydrogel. The hydrogel includes captured within it a therapeutic agent (65). The method of capture may be by various means, including photolabile bonds between the therapeutic agent (65) and the hydrogel (55). The therapeutic agent (65) is released from the hydrogel (55) by the application of energy to the hydrogel (55), such as by laser emitting wavelength (35) which resonates and breaks the photolabile bond. The released therapeutic agent (65) diffuses out of the hydrogel (55) into the liquid flowing within a lumen (60) of the catheter (20).
Appareil et procédés d'administration d'un médicament ou d'un composé dans un fluide s'écoulant à l'intérieur d'un tube ou d'un cathéter. Dans un mode de réalisation, un cathéter comprend une surface intérieure revêtue d'une matrice polymère telle qu'un hydrogel. Dans l'hydrogel est capturé un agent thérapeutique. Le procédé de capture peut être mis en oeuvre par divers moyens, notamment des liaisons photolabiles entre l'agent thérapeutique et l'hydrogel. L'agent thérapeutique est libéré de l'hydrogel par l'application d'une énergie sur l'hydrogel, telle que par un laser émettant une longueur d'onde résonnant et rompant la liaison photolabile. L'agent thérapeutique libéré se diffuse hors de l'hydrogel dans le liquide s'écoulant à l'intérieur d'une lumière du cathéter.
Biosynergetics Inc.
Macrae & Co.
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