Apparatus and process for determining the susceptibility of...

C - Chemistry – Metallurgy – 12 – N

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150/16.1

C12N 1/00 (2006.01)

Patent

CA 1051328

A B S T R A C T A process for determining the susceptibility of microorganisms to antibiotics involves introducing a diluted specimen into discrete quantities of a select- ive culture medium which favors a specific microorganism in that the microorganism is sustained by the medium and when so sustained will change the optical character- istics of the medium. Only the specific microorganism will alter the optical characteristics. Some of the discrete quantities are blended with know antibiotics, while at least one is not. If the specimen contains the microorganism favored by the selective medium, the optical characteristics of the discrete quantity of pure selective medium, that is the one without antibiotics, will change. If the antibiotics in any of the other discrete quantities are ineffective against the favored microorganisms, the optical characteristics of those quantities will likewise change. No change in the optical characteristics of a discrete quantity indicates that the favored microorganism is susceptible to the antibiotic in the quantity.

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