Apparatus for assay, synthesis and storage, and methods of...

C - Chemistry – Metallurgy – 12 – M

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C12M 1/34 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2619250

The invention features methods of making devices, or "platens", having a high- density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. Further, methods of making high density arrays of chemical, biochemical, and biological compounds, having many advantages over conventional, lower-density arrays are provided. The invention includes methods by which many physical, chemical or biological transformations can be implemented in se.pi.al or in parallel within each addressable through-hole of the devices. Additionally, methods of analyzing the contents of the array, including assaying of physical properties of the samples are included.

La présente invention concerne des procédés de fabrication de dispositifs ou de plateaux comportant un réseau très dense de trous traversants ainsi que des procédés de nettoyage et de reconditionnement/réarrangement des surfaces des plateaux. Cette invention porte également sur des procédés de fabrication de réseaux à haute densité de composés chimiques, biochimiques et biologiques qui présentent de nombreux avantages par rapport aux réseaux à faible densité classiques; et sur des procédés qui permettent de mettre en oeuvre une pluralité de transformations physiques, chimiques ou biologiques, en série ou en parallèle dans chaque trou traversant adressable des dispositifs. De surcroît, cette invention concerne des procédés d'analyse des contenus du réseau, y compris de détermination des propriétés physiques des échantillons.

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