Apparatus for delivering nitroglycerin to the skin, process...

Details Apparatus for delivering nitroglycerin to the skin, process... Apparatus for delivering nitroglycerin to the skin, process...

A - Human Necessities

61

K

167/159, 167/251

A61K 9/70 (2006.01) A61K 31/21 (2006.01) A61M 35/00 (2006.01) G01N 33/52 (2006.01)

Patent

CA 1329363

ABSTRACT OF THE DISCLOSURE An apparatus for the controlled delivery or release of nitroglycerin to human or animal skin is disclosed. The apparatus is preferably in plaster form with a nitroglycerin-impermeable backing layer, a single or multiple-part reservoir containing a pressure sensitive adhesive single or multiple-part reservoir comprising nitroglycerin in uniform or irregular distribution and, optionally, a removable protective layer impermeable to nitroglycerin. The reservoir is produced using hot melt pressure sensitive adhesives with a processing temperature of about 40 to 80°C, preferably about 40 to 60°C and in the particularly preferred manner about 40 to 55°C. The preferred use of the apparatus is for therapeutic purposes in human and veterinary medicine. A process for the production of the inventive apparatus is also disclosed.

575202

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