Apparatus for high throughput chemical reactions

B - Operations – Transporting – 01 – J

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B01J 19/24 (2006.01) C12M 1/38 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2677833

Apparatus, systems, chips, and methods of performing a large number of simultaneous chemical reactions are provided herein. The chips of the invention comprise addressable units that can be addressed according to the temperature of the reaction to be run. The subject apparatus, systems, and chips are particularly suited for performing polymerase chain reactions on thousands of nucleic acid sequences, up to and including sequences of an entire genome of an organism of interest.

L'invention concerne un appareil, des systèmes, des puces et des procédés permettant la mise en oeuvre d'un grand nombre de réactions chimiques simultanées. Selon l'invention, les puces comportent des unités adressables pouvant être repérées par une adresse en fonction de la température à laquelle la réaction doit être mise en oeuvre. L'appareil, les systèmes et les puces faisant l'objet de l'invention sont particulièrement appropriés pour la mise en oeuvre de réactions en chaîne par polymérase sur des milliers de séquences d'acides nucléiques, y compris des séquences d'un génome entier d'un organisme étudié.

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