Apparatus for measuring variations of extra-cellular...

G - Physics – 01 – N

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G01N 33/487 (2006.01) B01L 3/00 (2006.01) C12M 1/34 (2006.01)

Patent

CA 2658765

The invention proposes an apparatus of the type incl ud ing a su bstrate plate (1 2), a set ( 16) of m icroelectrodes arranged on the u pper face (14) of the su bstrate plate (1 2) and a tan k (24) wh ich is capable of conta in ing l iving cel ls and an perfusion l iq u id, and wh ich incl udes a vertical cyl ind rical lateral skirt (36) wh ich is open towards the top and wh ich surrounds an area incl ud ing sa id set (1 6) of m icroelectrodes; characterized in that the lateral skirt (36) is attached in a sealed and detachable way with respect to the substrate plate ( 12).

L'invention concerne un appareil d'un type incluant une plaque de substrat (12), un jeu (16) de microélectrodes disposées sur la face supérieure (14) de la plaque de substrat (12) et un réservoir (24) capable de contenir des cellules vivantes et un liquide de perfusion, et qui inclut une jupe verticale cylindrique latérale (36) qui est ouverte vers le haut et qui entoure une zone incluant ledit jeu (16) de microélectrodes ; la jupe latérale (36) étant fixée d'une manière étanche et détachable à la plaque de substrat (12).

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