Apparatus for screening compound libraries

Details Apparatus for screening compound libraries Apparatus for screening compound libraries

G - Physics

01

N

G01N 33/53 (2006.01) C12Q 1/68 (2006.01) G01N 30/46 (2006.01) G01N 30/72 (2006.01) G01N 33/538 (2006.01) G01N 33/543 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01) H01J 49/04 (2006.01) G01N 30/62 (2006.01)

Patent

CA 2240380

Disclosed are apparatus for screening compound libraries using frontal chromatography in combination with mass spectrometry to identify and rank those members of the library that bind to a target receptor. The apparatus of this invention also permit a compound library to be rapidly screened to determine if any member of the library has a higher affinity for the target receptor relative to a pre- selected indicator compound.

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