Apparatuses and methods to treat atherosclerotic plaques

A - Human Necessities – 61 – L

Patent

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A61L 31/14 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2665382

This invention comprises an apparatus for treating an atherosclerotic plaque in a coronary artery of a mammal by placing at or proximate to an entrance to the coronary artery and upstream of the vulnerable plaque, and an effective amount of a therapeutic agent for the treatment of the plaque. This invention comprises delivering a deposition of a therapeutic drug high in the coronary arterial tree for treatment of downstream vulnerable plaques. The invention also comprises slow release formulation and delivery of an apparatus that is totally degradable or removed and/or replaced.

L'invention concerne un appareil permettant de traiter une plaque d'athérosclérose dans une artère coronaire chez un mammifère en plaçant à proximité d'une entrée vers l'artère coronaire et en amont de la plaque vulnérable, une quantité efficace d'un agent thérapeutique destiné à traiter cette plaque. Cette invention consiste à apporter un dépôt de médicament thérapeutique à un niveau élevé de la ramification artérielle coronaire en vue de traiter en aval une plaque vulnérable. Cette invention concerne aussi une préparation à libération lente et l'apport d'un appareil totalement dégradable ou d'un appareil éliminé et/ou remplacé.

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