Application of new dna fragments as sequence coding for a...

C - Chemistry – Metallurgy – 12 – N

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195/1.2, 195/1.2

C12N 15/81 (2006.01) C07K 14/435 (2006.01) C07K 14/815 (2006.01) C12N 1/19 (2006.01) C12N 9/24 (2006.01) C12N 15/11 (2006.01) C12N 15/15 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2032153

L'invention concerne de nouveaux fragments d'ADN et leur application à titre de fragment d'ADN codant pour un pep- tide signal utile pour la sécrétion de proteines, ce peptide comprenant une séquence d'acides aminés qui présente un degré d'ho- mologie d'au moins 60 % avec la séquence d'acides aminés (I) ou (II), de préférence avec la séquence (II). Les séquences (I) et (II) sont comme suit: (I) Arg-Phe-Ser-Thr-Thr-Leu-Ala-Thr-Ala-Ala-Thr-Ala-Leu- Phe-Phe-Thr-Ala-Ser-Gln. (II) Arg-Phe-Ser- Thr-Thr-Leu-Ala-Thr-Ala-Ala-Thr-Ala-Leu-Phe-Phe-Thr-Ala-Ser-Gln-Val-Ser-Ala.

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