Application of oligonucleotides linked to an intercalating...

Details Application of oligonucleotides linked to an intercalating... Application of oligonucleotides linked to an intercalating...

C - Chemistry, Metallurgy

07

H

167/202, 195/1.1

C07H 21/00 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01)

Patent

CA 1321363

Application of oligonucleotides linked to an intercalating agent, especially as a drug Abstract: The invention relates to the application of oligonucleotide compounds linked to an intercalating agent for the selective blocking of a nucleic acid sequence, wherein these compounds consist of an oligonucleotide or an oligodeoxynucleotide consisting of a natural or modified nucleotide arrangement comple- mentary to the nucleic acid sequence to be selectively blocked, to which an intercalating group is bound through a covalent bond. These products are useful, in particular, as a drug.

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