Application of substances acting as cascade inhibitors of...

A - Human Necessities – 61 – K

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A61K 31/352 (2006.01) A61K 31/145 (2006.01) A61K 31/166 (2006.01) A61P 31/12 (2006.01) A61P 31/16 (2006.01)

Patent

CA 2405307

The invention relates to the use of substances that act as cascade inhibitors of the Raf/MEK/ERK signal cascade, in particular as MEK inhibitors, for producing a medicament for the preventive and anti-viral treatment of DNA and RNA viruses, in particular for the treatment of intranuclear replicating negative-strand RNA viruses, for example influenza or Borna disease viruses.

L'invention concerne des substances agissant en tant qu'inhibiteurs de la cascade de signaux Raf/MEK/ERK, notamment en tant qu'inhibiteurs de MEK, pour produire un médicament servant à la thérapie préventive et antivirale contre les virus à ADN et à ARN, en particulier contre les virus à ARN à brin négatif à réplication intranucléaire, tels que les virus de la grippe ou de la maladie de Borna.

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