Application of vasopressin antagonists for treating...

A - Human Necessities – 61 – K

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A61K 38/11 (2006.01) A61K 31/395 (2006.01) A61K 31/404 (2006.01) A61K 31/55 (2006.01) A61K 38/08 (2006.01) A61P 27/16 (2006.01)

Patent

CA 2309117

The invention relates to the application of at least one vasopressin receptor antagonist or mixture of such antagonists in order to treat disturbances or illnesses of the inner ear. These disturbances/illnesses can be connected to at least one of the following symptoms: vertigo, impairment of hearing or tinnitus. The symptoms can especially relate to those of so-called Ménièr's disease. According to the invention, especially vasopressin V2 receptor antagonists can be applied, whereby the antagonists can be peptidic or non- peptidic substances.

L'invention concerne l'utilisation d'au moins un antagoniste des récepteurs de la vasopressine ou de mélanges de tels antagonistes pour le traitement de troubles ou de maladies de l'oreille interne. Ces troubles/maladies peuvent être associés au moins à un des symptômes suivants: vertiges, surdité ou bourdonnement. Il peut en particulier s'agir de ce que l'on appelle la maladie de Ménière. Selon l'invention, on peut en particulier utiliser des antagonistes des récepteurs de la vasopressine V¿2?, ces antagonistes pouvant être des substances peptidiques ou non peptidiques.

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