C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/15 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) A61K 49/14 (2006.01) A61K 51/08 (2006.01) A61P 25/00 (2006.01) C07K 14/81 (2006.01)
Patent
CA 2597958
The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptides derived from aprotinin and from aprotinin analogs as well as conjugates and pharmaceutical compositions comprising these polypeptides or conjugates. The present invention also relates to the use of these polypeptide for transporting a compound or drug across the blood-brain barrier of a mammal and in the treatment and diagnosis of neurological diseases.
L~invention concerne des améliorations dans le domaine de l~administration de médicaments. En particulier, l~invention concerne des polypeptides dérivés de l~aprotinine et d~analogues d~aprotinine ainsi que des conjugués et des compositions pharmaceutiques renfermant ces polypeptides ou conjugués. La présente invention concerne également l~utilisation de ces polypeptides pour transporter un composé ou un médicament à travers la barrière sang-cerveau d~un mammifère et pour traiter et diagnostiquer des maladies neurologiques.
Beliveau Richard
Che Christian
Demeule Michel
Regina Anthony
Angiochem Inc.
Fasken Martineau Dumoulin Llp
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