Aptamer-based colorimetric sensor systems

Details Aptamer-based colorimetric sensor systems Aptamer-based colorimetric sensor systems

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2618485

The present invention provides an aptamer-based colorimetric sensor system for determining the presence and optionally the concentration of an analyte in a sample. Methods of utilizing the sensor system and kits that include the sensor also are provided. The sensor utilizes a linker and oligonucleotide functional ized particles to form an aggregate, which disaggregates in response to the analyte.

La présente invention concerne un système détecteur colorimétrique à base d'aptamère pour déterminer la présence et éventuellement la concentration d'un analyte dans un échantillon. L'invention concerne également les procédés d'utilisation du système détecteur et des trousses contenant ce détecteur. Le détecteur utilise un lieur et des particules à fonction oligonucléotidique pour former un ensemble qui se désagrège en réaction à l'analyte.

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