Aptamer for ngf and use thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/09 (2006.01) C07K 1/22 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2738129

Provided are an aptamer having an inhibitory activity against NGF; a complex containing an aptamer having a binding activity or inhibitory activity against NGF and a functional substance (e.g., affinity substances, labeling substances, enzymes, drug delivery vehicles, drugs and the like); a medicament, a diagnostic agent, a labeling agent and the like containing an aptamer having a binding activity or inhibitory activity against NGF, or a complex containing the aptamer and the functional substance; and the like.

L'invention porte sur : un aptamère présentant une activité d'inhibition sur le NGF; un complexe renfermant un aptamère présentant une activité de fixation au NGF ou présentant une activité d'inhibition sur le NGF et une substance fonctionnelle (par exemple, une substance d'affinité, une substance de marquage, une enzyme, un milieu d'administration de médicament ou un médicament); un agent pharmaceutique, un agent de diagnostic et un agent de marquage renfermant chacun un aptamère présentant une activité de fixation au NGF ou présentant une activité d'inhibition sur le NGF ou renfermant chacun un complexe renfermant l'aptamère et une substance fonctionnelle; et autres.

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