Aptamer-toxin molecules and methods for using same

Details Aptamer-toxin molecules and methods for using same Aptamer-toxin molecules and methods for using same

A - Human Necessities

61

K

A61K 51/06 (2006.01) A61K 38/00 (2006.01) A61K 45/00 (2006.01) A61K 47/30 (2006.01) A61K 47/48 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2487809

Materials and methods are provided to prepare therapeutic conjugates for the treatment of proliferative diseases. The therapeutic conjugates of the invention comprise a targeting moiety conjugated to a therapeutic moiety. The therapeutic moiety of the conjugates of the present invention have a cytotoxic effect and are useful in the treatment of proliferative diseases.

L'invention concerne des matériaux et procédés pour préparer des conjugués thérapeutiques pour le traitement de maladies prolifératives. Les conjugués thérapeutiques de l'invention comprennent un groupe fonctionnel de ciblage conjugué à un groupe fonctionnel thérapeutique. Le groupe fonctionnel thérapeutique des conjugués de la présente invention a un effet cytotoxique et est utile dans le traitement des maladies prolifératives.

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