Aptamers that bind thrombin with high affinity

Details Aptamers that bind thrombin with high affinity Aptamers that bind thrombin with high affinity

A - Human Necessities

61

K

A61K 48/00 (2006.01)

Patent

CA 2617782

The invention provides aptamers capable of binding to thrombin useful as therapeutics for and diagnostics of coagulation related disorders and/or other diseases or disorders in which thrombin has been implicated. The invention further provides materials and methods for the administration of aptamers capable of binding to thrombin.

La présente invention se rapporte à des aptamères pouvant se lier à la thrombine, qui sont utiles pour traiter et diagnostiquer des troubles liés à la coagulation et/ou d'autres maladies ou troubles mettant en jeu la thrombine. L'invention a également trait à des matériaux et à des méthodes permettant d'administrer lesdits aptamères pouvant se lier à la thrombine.

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