A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) C07K 14/715 (2006.01) C08G 63/91 (2006.01)
Patent
CA 2623424
The present invention provides materials and methods to treat immune disease in which cytokines are involved in pathogenesis. The materials and methods of the present invention are useful in the treatment of autoimmune diseases. The materials and methods of the present invention are directed to nucleic acid ligands capable of binding to human IL-23 and/or human IL- 12 cytokines and thus modulate their biological activity and are useful as therapeutic agents in immune, auto-immune and cancer therapeutics.
La présente invention concerne des substances et des méthodes de traitement de maladies auto-immunes dans la pathogénèse desquelles sont impliquées des cytokines. Ces substances et méthodes conviennent pour le traitement de maladies auto-immunes. Sont concernés de ligands d'acides nucléiques capables de se lier aux cytokines humaines IL-23 et/ou aux cytokines humaines IL- 12 et donc de moduler leur activité biologique. Ces ligands sont utiles comme agents thérapeutiques dans le traitement des maladies auto-immunes et du cancer.
Diener John L.
Epstein David
Ferguson Alicia
Hamaguchi Nobuko
Lagasse Daniel H. A.
Archemix Corp.
Diener John L.
Epstein David
Ferguson Alicia
Hamaguchi Nobuko
LandOfFree
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