Aquaretic and natriuretic polypeptides lacking vasodilatory...

Details Aquaretic and natriuretic polypeptides lacking vasodilatory... Aquaretic and natriuretic polypeptides lacking vasodilatory...

C - Chemistry, Metallurgy

07

K

C07K 14/00 (2006.01)

Patent

CA 2662453

This document provides aquaretic and natriuretic polypeptides. For example, this document provides polypeptides having aquaretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have aquaretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing aquaretic and/or natriuretic activities within a mammal.

Polypeptides aquarétiques et natriurétiques dépourvus d'activité vasodilatatoire. On décrit par exemple des polypeptides ayant des activités aquarétiques et/ou natriurétiques. Dans certains cas, il s'agit d'un polypeptide pouvant avoir des activités aquarétiques et natriurétiques, tout en n'ayant pas le pouvoir de réduire la pression artérielle. Enfin, l'invention concerne des procédés et des matériaux permettant d'induire des activités aquarétiques et/ou natriurétiques chez un mammifère.

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