Aqueous aerosol preparation

Details Aqueous aerosol preparation Aqueous aerosol preparation

A - Human Necessities

61

K

A61K 9/107 (2006.01) A61K 9/00 (2006.01) A61K 9/12 (2006.01)

Patent

CA 2542666

Disclosed are sterile aqueous preparations that are to be inhaled as an aerosol and contain an active substance, a nonionic surfactant, and a phospholipid. Said preparations are suitable for administering poorly soluble active substances by way of inhalation in the form of colloidal solutions and can also be used for administering bad-tasting active substances that irritate the mucus and cause cough or bronchoconstrictions. The inventive preparations can be nebulized by means of conventional devices and are preferably used in pediatrics.

L'invention concerne des préparations aqueuses stériles destinées à être inhalées sous forme d'aérosol, lesquelles comprennent un principe actif, un tensioactif non ionique et un phospholipide. Ces préparations conviennent pour l'administration par inhalation de principes actifs difficilement solubles sous forme de solutions colloïdales. Elles peuvent en outre être utilisées pour l'administration de principes actifs ayant mauvais goût, irritant la muqueuse, et déclenchant la toux et la bronchoconstriction. Ces préparations peuvent être atomisées à l'aide d'appareils usuels et être utilisées de façon avantageuse en pédiatrie.

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