Aqueous composition comprising thiazole derivative

Details Aqueous composition comprising thiazole derivative Aqueous composition comprising thiazole derivative

A - Human Necessities

61

K

A61K 31/426 (2006.01) C07D 277/38 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2558135

The present invention provides an aqueous composition comprising a thiazole derivative of the formula (I): R1-NH-X-Y-Z (I) wherein each symbol is as defined above, or a parmaceutically acceptable salt thereof, and an additive selected from the group consisting of polyol, sugar, sugar alcohol, boric acid or its salt, and water. The aqueous composition is very stable and can be stored for a long time.

La présente invention porte sur une composition aqueuse comprenant un dérivé de thiazole de la formule (I) : R?1¿-NH-X-Y-Z (I) dans laquelle chaque symbole est tel que défini ci-dessus, ou un sel pharmaceutiquement acceptable de celui-ci, et un additif sélectionné parmi le groupe consistant de polyol, sucre, alcool de sucre, acide borique ou son sel, et de l~eau. La composition aqueuse est très stable et peut être conservée pendant une longue période.

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