Aqueous compositions containing ciprofloxacine, and related...

A - Human Necessities – 61 – K

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A61K 31/496 (2006.01) A61P 27/16 (2006.01)

Patent

CA 2200760

Aqueous compositions containing ciprofloxacine and corresponding use and process, said composition comprising from 0.12-0.6 g/ml of chlorohydrate monohydrate of ciprofloxacine (equivalent to 0.1-0.5% of free base); 0.5-3.0 g/ml of a buffer system capable of maintaining the pH between 4 and 5; 0.05-0.3 g/ml of a non ionic surface--active agent; from 0.5-2.0 g/ml of a thickening agent; and the rest to 100 ml of water.

Compositions aqueuses contenant du ciprofloxacine, utilisation et procédé correspondants; les compositions comprennent de 0,12 à 0,6 g/100 ml de chlorohydrate monohydrate de ciprofloxacine (équivalent à 0,1-0,5 % de base libre); de 0,5 à 3,0 g/100 ml d'un système tampon pouvant fixer le pH entre 4 et 5; de 0,05 à 0,3 g/100 ml d'un agent tensioactif non ionique; de 0,5 à 2,0 g/100 ml d'un agent épaississant, et le reste étant de l'eau en quantité suffisante pour 100 ml.

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