Aqueous fludarabine phosphate composition

A - Human Necessities – 61 – K

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A61K 31/7076 (2006.01) A61K 9/00 (2006.01) A61K 31/70 (2006.01) A61K 47/02 (2006.01) A61K 47/26 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2487070

This invention is directed towards a ready-to-use aqueous composition of fludarabine phosphate. In one embodiment, the invention is directed to an aqueous fludarabine phosphate composition which comprises fludarabine phosphate, a base, and water. The concentration of fludarabine phosphate in the composition may be between about 0.5 mg/mL and about 50 mg/mL. The pH of the composition may be between about 5.5 and about 7.1.

La présente invention se rapporte à une composition aqueuse, prête à l'emploi, de phosphate de fludarabine. Dans un mode de réalisation, l'invention se rapporte à une composition aqueuse de phosphate de fludarabine qui contient du phosphate de fludarabine, une base et de l'eau. La concentration du phosphate de fludarabine dans la composition peut être comprise entre 0,5 mg/mL environ et 50 mg/mL environ. Le pH de la composition peut être compris entre 5,5 environ et 7,1 environ.

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