Aqueous formulations containing a...

A - Human Necessities – 61 – K

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A61K 31/70 (2006.01) A61K 9/08 (2006.01) A61K 31/445 (2006.01) A61K 47/48 (2006.01) C08B 37/00 (2006.01) C08B 37/16 (2006.01)

Patent

CA 1328078

ABSTRACT AQUEOUS FORMULATIONS CONTAINING A PIPERIDINYLCYCLOPENTYLHEPTENOIC ACID DERIVATIVE Aqueous formulations comprising [1R-[1.alpha.(Z),2.beta.,3.beta.,5.alpha.]]-(+)-7-[5- [[(1,1'-biphenyl)-4-yl]methoxy]-3-hydroxy-2-(1-piperidinyl) cyclopentyl]-4-heptenoic acid or its hydrochloride salt and an unsubstituted or substituted .alpha.-, .beta.- or .gamma.- cyclodextrin have been found which are particularly useful in the treatment or prophylexis of conditions mediated by thromboxene A2. Suitable aqueous formulations include injections, oral preparations such as syrups and capsules and inhalation preparations.

586606

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