Aqueous ophthalmic compositions containing anionic...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 31/277 (2006.01)

Patent

CA 2758858

The present invention is directed to the provision of multi-dose, ophthalmic compositions. The compositions possess sufficient antimicrobial activity to satisfy USP preservative efficacy requirements, as well as similar preservative standards (e.g., EP and JP). The compositions include a balance of ingredients that allow for the formation of ophthalmic compositions that include an anionic drug and exhibit desired characteristics such as stability, preservation efficacy, desired pH, desired osmolality, combinations thereof or the like.

La présente invention porte sur la fourniture de compositions ophtalmiques à doses multiples. Les compositions possèdent une activité antimicrobienne suffisante pour satisfaire les exigences d'efficacité de conservation USP, ainsi que des standards de conservation similaires (par exemple européens et japonais). Les compositions comprennent un équilibre d'ingrédients qui permettent la formation de compositions ophtalmiques qui comprennent un médicament anionique et présentent des caractéristiques voulues telles que la stabilité, l'efficacité de conservation, le pH voulu, l'osmolalité voulue, des combinaisons de celles-ci ou autres.

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