A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4704 (2006.01) A61K 9/08 (2006.01) A61K 9/10 (2006.01) A61K 47/32 (2006.01) A61K 47/34 (2006.01) A61K 47/38 (2006.01) A61P 27/02 (2006.01)
Patent
CA 2584017
The invention provides an ophthalmic product containing rebamipide, which has a transparency enough to be agreeable feeling on using it and has neutral to weakly acidic pH not to injury of the keratoconjunctiva of a patient suffering from dry eye. An aqueous suspension of crystalline rebamipide which has an improved transparency is provided by adding an aqueous solution of rebamipide dissolved by a base such as sodium hydroxide or an aqueous solution of a salt of rebamipide to an aqueous acidic solution such as hydrochloric acid containing at least one of the compounds selected from water-soluble polymers and surfactants, and mixing them.
L~invention concerne un produit ophtalmique contenant du rébamipide, suffisamment transparent pour conférer une sensation agréable, avec un pH neutre faiblement acide pour ne pas blesser la conjonctive kératine d~un patient ayant les yeux secs. L~invention porte sur une suspension aqueuse de rébamipide cristallin dont la transparence est améliorée en ajoutant une solution aqueuse de rébamipide dissout par une base comme de l~hydroxyde de sodium ou une solution aqueuse d~un sel de rébamipide à une solution acidifère aqueuse comme un acide chlorhydrique contenant au moins l~un des composés sélectionnés parmi les polymères solubles dans l~eau et les tensioactifs, avant de les mélanger.
Hiraoka Shogo
Ishikawa Shinichi
Matsuda Takakuni
Tomohira Yuso
Kirby Eades Gale Baker
Otsuka Pharmaceutical Co. Ltd.
LandOfFree
Aqueous ophthalmic suspension of crystalline rebamipide does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aqueous ophthalmic suspension of crystalline rebamipide, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aqueous ophthalmic suspension of crystalline rebamipide will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1909903