Aqueous pharmaceutical compositions containing borate-polyol...

A - Human Necessities – 61 – K

Patent

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A61K 9/00 (2006.01) A61K 31/045 (2006.01) A61K 31/14 (2006.01) A61K 31/215 (2006.01) A61K 31/535 (2006.01) A61K 31/5575 (2006.01) A61K 33/40 (2006.01) A61K 47/02 (2006.01) A61K 47/10 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2717679

The present invention is directed to the provision of multi-dose, ophthalmic compositions. The compositions pos-sess sufficient antimicrobial activity to satisfy USP preservative efficacy requirements, as well as similar preservative standards (e.g., EP and JP). The compositions include at two different polyols in conjunction with borate, a preservative or both.

Cette invention concerne l'élaboration de compositions ophtalmiques, multi-doses. Les compositions possèdent une activité antimicrobienne suffisante pour satisfaire les critères d'efficacité de la conservation USP, et autres normes de conservation similaires (par exemple, EP et JP). Les compositions comprennent au moins deux polyols différents avec un borate, un conservateur, ou les deux.

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