Aqueous solution for use in the treatment of degenerative or...

A - Human Necessities – 61 – K

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A61K 31/125 (2006.01) A61K 9/08 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2297998

The invention concerns an aqueous solution capable of being injected by perinodular delivery or inhaled for use in the treatment of degenerative or autoimmune diseases or as immunomodulatory agent. Said solution is prepared by reacting camphor on ammonium hydroxide. The resulting product is then suspended in a saline solution. Said preparation having a basic pH is then neutralised with nitric acid. The resulting aqueous solution has pharmacological properties since it is an analogue of human cytokines, which makes it useful for treating degenerative or autoimmune diseases and/or as an immunomodulatory agent.

L'invention a pour objet une solution aqueuse qui est injectable par voie périnodulaire ou inhalable et est utilisable pour le traitement de maladies dégénératives ou autoimmunes ou comme agent immunomodulateur. Cette solution est préparée en faisant réagir du camphre sur de l'hydroxyde d'ammonium. Le produit ainsi obtenu est ensuite mis en suspension dans une solution saline. Cette préparation ayant un pH basique est alors neutralisée par l'acide nitrique. La solution aqueuse ainsi préparée présente des propriétés pharmacologiques puisqu'elle mime les cytokines humaines. Ceci la rend utilisable pour le traitement de maladies dégénératives ou autoimmunes et/ou comme agent immunomodulateur.

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