Aqueous suspension preparations with excellent redispersibility

Details Aqueous suspension preparations with excellent redispersibility Aqueous suspension preparations with excellent redispersibility

A - Human Necessities

61

K

A61K 9/10 (2006.01) A61K 9/00 (2006.01) A61K 9/08 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2289618

A aqueous suspension preparations of hardly soluble drugs containing water soluble polymers at a concentration within a range from the concentration at which the decrease in the surface tension of the liquid preparations is initiated to the concentration at which such decrease is terminated. These preparations can be easily redispersed and undergo neither aggregation of the dispersed particles nor caking. The excellent redispersibility of these preparations makes them useful as injections, eye drops, nasal drops, drugs for internal use, lotions, etc.

L'invention concerne des préparations à base de suspensions aqueuses utilisant des médicaments à peine solubles qui comprennent des polymères hydrosolubles dont la concentration est comprise entre, d'une part, une valeur qui correspond au début d'une baisse de la tension superficielle des préparations liquides et, d'autre part, une valeur à laquelle cette baisse prend fin. Ces préparations sont aptes à une redispersion aisée et ne subissent ni d'agglutination, ni d'agrégation des particules dispersées. Les excellentes propriétés de redispersion de ces préparations permettent de les utiliser en tant qu'injections, collyres, gouttes pour le nez, médicaments pour l'usage interne, lotions, etc.

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