Aqueous suspensions of tmc278

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 31/00 (2006.01)

Patent

CA 2654115

This invention concerns pharmaceutical compositions for administration via intramuscular or subcutaneous injection, comprising micro- or nanoparticles of the NNRTI compound TMC278, suspended in an aqueous pharmaceutically acceptable carrier, and the use of such pharmaceutical compositions in the treatment and prophylaxis of HIV infection.

La présente invention concerne des compositions pharmaceutiques destinées à être administrées par injection intramusculaire ou sous-cutanée et contenant des microparticules ou des nanoparticules du composé inhibiteur non nucléosidique de la transcriptase inverse (NNRTI) TMC278, en suspension dans un support aqueux pharmaceutiquement acceptable. L'invention concerne également l'utilisation de telles compositions pharmaceutiques pour le traitement et la prophylaxie d'une infection par le VIH.

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