Arabinose- and xylose-fermenting saccharomyces cerevisiae...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 1/19 (2006.01) C12N 1/18 (2006.01) C12N 15/81 (2006.01) C12P 7/08 (2006.01)

Patent

CA 2602084

The present invention relates to a S. cerevisiae strain expressing both arabinose and xylose utilization pathways, and in particular to a S. cerevisiae strain fermenting both arabinose and xylose to ethanol, and more particularly a S. cerevisiae strain with overexpression or upregulation of xylose- or aldose reductase (XR, AR) with xylitol dehydrogenase (XDH) together with overexpression or upregulation of genes forming an arabinose utilization pathway. The invention encompasses both laboratory and industrial strain having these properties.

La présente invention concerne une souche de S. cerevisiae qui exprime les mécanismes d'utilisation de l'arabinose et du xylose et notamment une souche de S. cerevisiae qui fait fermenter l'arabinose et le xylose en éthanol, et plus particulièrement une souche de S. cerevisiae présentant une surexpression ou une régulation à la hausse de la xylose-réductase ou de l'aldose-réductase (XR, AR) avec une xylitol-déshydrogénase (XDH) en même temps que la surexpression ou que la régulation à la hausse de gènes formant un mécanisme d'utilisation de l'arabinose. Cette invention se rapporte aux souches de laboratoire et de l'industrie qui présentent ces propriétés.

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