Aralkyltetrahydropyridines, their preparation and...

C - Chemistry – Metallurgy – 07 – D

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C07D 211/70 (2006.01) A61K 31/4418 (2006.01) A61K 31/444 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2460822

The invention concerns compounds of formula (I), wherein: X represents N or CH; R1 represents a hydrogen or halogen atom of a CF3 group; n is an integer from 1 to 5; A represents a partly saturated bicyclic or tricyclic carbon compound, as well as their salts or solvates, their N--oxides, pharmaceutical compositions containing them, a method for preparing them and synthesis intermediates in said method.

La présente invention concerne des composés de formule (I), dans laquelle X représente N ou CH; R¿1? représente un atome d'hydrogène ou d'halogèene ou un groupe CF¿3?; n est un entier de 1 à 5; A représente un bi- ou tri-cycle carbonné partiellement saturé, ainsi que leurs sels ou solvates, leurs N-oxyes, les compositions pharmaceutiques les contenant, un procédé pour leur préparation et des intermédiaires de synthèse dans ce procédé.

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