Aralykyl (arylethynyl) aralkyl amines and their use as...

Details Aralykyl (arylethynyl) aralkyl amines and their use as... Aralykyl (arylethynyl) aralkyl amines and their use as...

C - Chemistry, Metallurgy

07

C

167/179, 260/602

C07C 211/23 (2006.01) A61K 31/135 (2006.01) C07C 45/58 (2006.01) C07C 45/62 (2006.01) C07C 45/63 (2006.01) C07C 45/68 (2006.01) C07C 45/74 (2006.01) C07C 49/223 (2006.01) C07C 49/255 (2006.01) C07C 59/64 (2006.01) C07C 217/62 (2006.01) C07D 303/40 (2006.01) C07F 1/08 (2006.01)

Patent

CA 1292747

ARALKYL (ARYLETHYNYL)ARALKYL AMINES AND THEIR USE AS VASODILATORS AND ANTIHYPERTENSIVES ABSTRACT Acetylenes of the formula (I): Image (I) wherein Y, m, R1, R2, q, Alk, R3, n and R4 are as defined herein and Ar1 and Ar2 are aromatic, including the salts and ammonium derivatives of formula (I), in treating angina, hypertension and cardiac arrhythmias. Pharma- ceutical compositions, methods of use and synthesis and novel intermediates are also part of the invention. MN-416

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