Argatroban formulation comprising an acid as solubilizer

Details Argatroban formulation comprising an acid as solubilizer Argatroban formulation comprising an acid as solubilizer

A - Human Necessities

61

K

A61K 9/08 (2006.01) A61K 31/47 (2006.01) A61K 47/12 (2006.01)

Patent

CA 2617920

An aqueous, stable, sterile pharmaceutical composition of the thrombin inhibitor argatroban in a solution containing an acid to solubilize the argatroban, substantially free from dehydrated alcohol is described, as well as method for its preparation.

L'invention concerne une composition pharmaceutique aqueuse, stable et stérile de l'inhibiteur de thrombine argatroban en solution contenant un acide pour solubiliser l'argatroban, cette composition étant sensiblement exempte d'alcool déshydraté. L'invention concerne en particulier un procédé de préparation de cette composition.

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