Arginine heteromers for topical administration

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 311/04 (2006.01) A61K 8/365 (2006.01) A61K 8/67 (2006.01) A61K 47/48 (2006.01) A61Q 19/00 (2006.01) C07C 57/03 (2006.01) C07C 401/00 (2006.01) C07C 403/00 (2006.01) C07D 307/62 (2006.01)

Patent

CA 2635784

The invention is directed to a strategy for providing therapeutic or cosmetic benefit to skin by topically applying arginine chemically bound to a second (non-oligo arginine) compound in order to increase transepithelial delivery of arginine through a combination of increased solubility and flux across the skin. The arginine heteromers ofthe invention can add other complementary or beneficial properties for the skin beyond those that are arginine-related.

La présente invention concerne une stratégie pour produire un avantage thérapeutique ou cosmétique sur la peau par application locale d'arginine chimiquement liée à un second composé (non-oligo-arginine) afin d'augmenter l'administration transépithéliale d'arginine par l'intermédiaire d'une combinaison de solubilité et de flux augmentés à travers la peau. Les hétéromères d'arginine de l'invention peuvent ajouter d'autres propriétés complémentaires ou bénéfiques pour la peau en plus de celles associées à l'arginine.

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