Arginine inactivation of viruses

Details Arginine inactivation of viruses Arginine inactivation of viruses

C - Chemistry, Metallurgy

12

N

C12N 7/06 (2006.01)

Patent

CA 2742817

The present invention pertains to methods of using arginine to inactivate or reduce the infectious titer of enveloped viruses potentially present in biological compositions produced by eukaryotic cells (such as a antibodies or other therapeutic proteins). In some embodiments, inactivation or reduction of viral titers by exposure to arginine is achieved in a neutral (pH ~7) or near neutral (~pH 6 to ~pH 8) environment.

La présente invention concerne des procédés dutilisation de larginine pour inactiver ou réduire le titre infectieux de virus à enveloppe potentiellement présents dans des compositions biologiques produites par des cellules eucaryotes (telles que des anticorps ou dautres protéines thérapeutiques). Dans certains modes de réalisation, linactivation ou la réduction de titres viraux par exposition à larginine est réalisée dans un environnement neutre (pH ~7) ou proche de la neutralité (~pH 6 à ~pH 8).

Affiliated with

Also associated with

Rating

Arginine inactivation of viruses does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Arginine inactivation of viruses, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Arginine inactivation of viruses will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1882637