Aromatase inhibition to enhance assisted reproduction

Details Aromatase inhibition to enhance assisted reproduction Aromatase inhibition to enhance assisted reproduction

A - Human Necessities

61

K

A61K 38/24 (2006.01) A61K 31/4196 (2006.01) A61K 31/5685 (2006.01) A61P 5/24 (2006.01) A61P 15/08 (2006.01)

Patent

CA 2444932

The use of at least one aromatase inhibitor in the production of a medicament for improving the implantation and pregnancy rates for a female undergoing assisted reproduction treatment, which comprises one or more daily doses of an aromatase inhibitor (AI) for administration during assisted reproduction cycles or ovarian stimulation cycles, wherein the doses of AI are selected from amounts effective to reduce serum estradiol levels. Also disclosed are related pharmaceutical preparations and packages.

La présente invention concerne l'utilisation d'au moins un inhibiteur d'aromatase pour la production d'un médicament destiné à améliorer les taux de nidation et de grossesse chez une femme soumise à un traitement de reproduction assistée, qui comprend une ou plusieurs doses quotidiennes d'un inhibiteur d'aromatase (AI) destinées à être administrées au cours de cycles de reproduction assistée ou de cycles de stimulation ovarienne, les doses d'AI étant sélectionnées parmi des quantités efficaces pour réduire les niveaux d'estradiol de sérum. L'invention concerne également des préparations et des conditionnements pharmaceutiques associés.

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