Aromatic and heterocyclic derivatives of phytosterols and/or...

Details Aromatic and heterocyclic derivatives of phytosterols and/or... Aromatic and heterocyclic derivatives of phytosterols and/or...

C - Chemistry, Metallurgy

07

J

C07J 43/00 (2006.01) A61K 31/58 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2376733

Novel phytosterol and/or phytostanol derivatives, including salts thereof, are represented by general formulae (I or II) wherein R is a phytosterol or phytostanol moiety; R2 is oxygen or hydrogen (H2) and R3 is an aromatic or heterocyclic unit. These derivatives are effective in treating and preventing cardiovascular disease and its underlying conditions including hyperlipidemia.

L'invention concerne de nouveaux dérivés de phytostérol et/ou de phytostanol, y compris leurs sels, représentés par les formules générales (I ou II), dans lesquelles R représente un groupe phytostérol ou phytostanol, R2 représente un oxygène ou un hydrogène (H2) et R3 représente une unité aromatique ou hétérocyclique. Ces dérivés sont efficaces dans la prévention et le traitement de l'affection cardio-vasculaire ainsi que de ses états sous-jacents, tels que l'hyperlipidémie.

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