Aromatic derivatives and iron complexes thereof for the use...

C - Chemistry – Metallurgy – 07 – D

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C07D 311/22 (2006.01) A61K 31/12 (2006.01) A61K 31/352 (2006.01) A61P 7/06 (2006.01) A61P 39/04 (2006.01) C07C 49/82 (2006.01)

Patent

CA 2348380

The present invention is directed to aromatic derivatives of formula (I), wherein: R1 is (a), wherein R3 and R4 are selected from between H and OH, provided that R3 and R4 are not simultaneously H, and R2 is H; or R1 and R2 taken together, are (b), wherein R5 is selected from between CH3 and (CH2)5OH, to the iron complexes thereof, and to their use for the preparation of pharmaceutical compositions for the normalisation of iron level.

L'invention concerne des dérivés aromatiques de formule (I), dans laquelle R1 est (a), R3 et R4 étant choisis entre H et OH, à condition qu'ils ne soient pas simultanément H, et R2 est H; ou bien R1 et R2 ensemble sont (b), R5 étant choisi entre CH3 et (CH2)5OH. L'invention concerne également les complexes ferriques desdits dérivés et leur utilisation pour la préparation de compositions pharmaceutiques destinées à normaliser la sidérémie.

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