Aromatic derivatives comprising an aminoalkoxy chain, the...

C - Chemistry – Metallurgy – 07 – D

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260/578.2, 260/6

C07D 295/04 (2006.01) C07C 45/54 (2006.01) C07C 45/63 (2006.01) C07C 45/67 (2006.01) C07C 45/71 (2006.01) C07C 205/45 (2006.01) C07D 295/092 (2006.01) C07D 319/18 (2006.01)

Patent

CA 1197243

ABSTRACT New aromatic derivatives having an activity antagonistic to calcium and corresponding to formula: Image (I) in which: - A represents a chain having any one of the following structures: Image - Ar represents a group of structure: Image - n takes the value 1 or 2 when R is different from H; - m takes the value 2 or 3. These new aromatic derivatives and their pharmaceutically acceptable salts are useful in the treatemnt of afflictions related to a disturbance of the intra and extra cellular movements of calcium and particularly troubles of the cardiovascular system, particularly as antiangorous, antirhythmic, antihypertension agents and vasodilators.

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