C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/578.2, 260/6
C07D 295/04 (2006.01) C07C 45/54 (2006.01) C07C 45/63 (2006.01) C07C 45/67 (2006.01) C07C 45/71 (2006.01) C07C 205/45 (2006.01) C07D 295/092 (2006.01) C07D 319/18 (2006.01)
Patent
CA 1197243
ABSTRACT New aromatic derivatives having an activity antagonistic to calcium and corresponding to formula: Image (I) in which: - A represents a chain having any one of the following structures: Image - Ar represents a group of structure: Image - n takes the value 1 or 2 when R is different from H; - m takes the value 2 or 3. These new aromatic derivatives and their pharmaceutically acceptable salts are useful in the treatemnt of afflictions related to a disturbance of the intra and extra cellular movements of calcium and particularly troubles of the cardiovascular system, particularly as antiangorous, antirhythmic, antihypertension agents and vasodilators.
418154
Bourgery Guy
Lacour Alain
Pourrias Bernard
Santamaria Raphael
Delalande S.a.
Gowling Lafleur Henderson Llp
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